Short notes of enzymes :-classfication,nomenclature,induce model. ~ Statusdeewane

ENZYMES;- enzyme are organic molecules is living organism and catalyse biochemical reaction.
NATURE OF ENZYME:-all enzyme are protein nature but all protein not enzyme.

HOLOENZYMES:-some enzyme are organic and inorganic conjucatedprotein.
*the conjucated protein part apoenzymes,non protein part prothetic enzymes.

ENZYMES CO-FACTOR:-
two type of co-factor
1-ORGANIC
2-INORGANIC

*organic contain co-enzyme and prosthetic enzyme.
*inorganic contain zn++,mg++,cu++

CO-ENZYMES:-co-enzymes are loosly attached to the apoenzyme.
exp-NAD,NADP

PROSTHETIC ENZYMES:-prosthetic enzymes are firmly attached to apoenzymes.
exp-FAD

Enzymes classification
__________|_____________
| |
intracellular extracellular
(endoenzyme) (exoenzymes)
| |
Secrete in cell secrete outside of cell

NOMENCLATURE:-nomenclature of enzymes devied into 6 class.
-more than enzymes endind look like ASE.
1 OXIREDUCTASE
2 TRANSFERASE.
3 HYDROLASES
4 LYASES
5 ISOMEASES
6.LIGASES

CONCEPT OF ACTIVE SITE;-
it is part of enzymes,two part of enzymes.

*CATALYSE SITE:-part of active site
*BLINDINK SITE:-part of active site and blind substrate.

SUBSTRATE:-these substance enztion is called substrate.

*LOCK AND KEY :-
[ ] as the name implies shaped of the active site and substrateare complementry like that of lock and key in this model.comlementry nature of active site and substrate shape allow formation of tight enzyme substrate complex to yield product and free enzyme.however this model fails to explain reversible enzymes catalyzed reaction due to rigid shape of active site.

Lock and key model

INDUCED MODEL:-
*it is advanced model.
*in this model enzymes surface are flexible.
*substrate come to the enzymes than occurs changing.
*enzymes surface same to the substrate surface.